Invited Speakers

Noorhafiza MUHAMMAD
Dean of School of Manufacturing Engineering, Universiti Malaysia Perlis, MALAYSIA

Noorhafiza Muhammad holds a Phd in Mechanical Engineering specializing in Laser Processing from The University of Manchester, United Kingdom. She is an associate professor and a Dean of the School of Manufacturing Engineering, Universiti Malaysia Perlis, Malaysia. She is a fellow researcher at the Centre of Excellence Geopolymer & Green Technology (CeGeoGTech). She has published a quite number of publications in renowned international conferences and scientific journals. Her research interests are in the field of manufacturing processes (laser processing), materials characterization, biodegradable polymer and materials. She has displayed outstanding reseach work and has obtained local and international scientific recognition through her research to the . She has introduced different approaches/techniques to aid cut quality improvement in laser cutting processes for stent applications.

*     *

The use of coronary stent is subjected to its compatibility and integration with the biological environment where it is implanted. The compatibility refers to material and tissue interactions. These characteristics have to be tested and appraised in an array of in vivo and in vitro experiments. There are three main rationales: 1. Laser surface texturing: By far, the vast majority of coronary stents are produced by laser processing. The advantage of using lasers against conventional methods is the ability to manufacture stents with the highest speed, precision and quality in order to meet the stringent requirements for implantation in the human body. 2. Surface modification on stents surface to modulate the cells response and enhance biocompatibility: Coronary artery disease is the leading cause of death, for both men and women worldwide. The suffering from the disease and the death would give social and economic impact to the country. It is crucial to establish a high biocompatibility implant device which require optimal after implant medical therapy. The ideal stent surface has to be established to enhance the biocompatibility and reduce the risk of restenosis and late thrombosis. 3. Low cost (affordable) stent with high performance: It is found that the endothelialisation is partially growth at the stents strut after the implantation. The endothelial dysfunction failed to serve as anticoagulant to prevent blood clot. The risk of restenosis after implantation of bare metal stents (BMS) encouraged the emergence of drug eluting stents (DES). However, high cost of DES (3 to 4 times expensive than bare metal stents) make it less favorable compared to BMS. Thus, the motivation is to facilitate faster endothelialisation on bare metal stent which could generate an appropriate response with the tissue in the biological environment with superior performance compared to DES.

Catalin POPA
Head of Biomaterials Research Group
Technical University of Cluj-Napoca, ROMANIA

Dr. Cătălin Popa is a Professor in the Department of Materials Science and Engineering in the Technical University of Cluj-Napoca, Head of Biomaterials Research Group and President of Advanced Materials, Micro and Nanotechnologies – ADMATECH Cluster. Dipl. Engineer since 1986, he worked at the beginning of the career as a design engineer in several companies, bringing the acquired expertise to the Biomaterials research field. Doctor of Engineering since 1997, he benefited of a NATO / Royal Society Fellowship in the University of Nottingham (2000) and was involved in numerous research projects in the UK, some of them in IRC in Biomedical Materials, QMUL, and Rutherford Appletopn Laboratory, together to the 27 research contracts with Romanian public funding bodies. He published more than 115 papers, 7 books and patented 4 inventions. The Biomaterials Research Group he leads focuses on Tissue Engineering scaffolds, drug delivery systems and medical implants / devices.

*     *

Drug delivery systems are suitable for numerous medical applications where the classical administration methods lead to either excessive stressing of kidneys / liver / heart or to ineffectiveness due to degradation, poor water solubility or lack of membrane permeability for the active agent. By an appropriate design of multilayered microcapsules, application – tailored delivery systems can be obtained, showing optimal characteristics both from the drug nature and concentration point of view, as well as for the release triggering mechanism / time profile. We have developed microcapsules with a BSA gel core and natural polyelectrolites (chitosan and k-carrageenan) complex multilayer shell using the layer-by-layer (Lbl) deposition method. Their architecture was tailored for applications such as Tissue Engineering of hard / soft tissues, smart dressing for healing of difficult wounds or targeted chemotherapy of non – resecable cancerous tumors. Interesting results were obtained by loading the microcapsules with Curcumin (anti-oxidant, anti-cancer and anti-inflammatory agent), Tetracyclin (antibiotic with wide spectrum against many gram-negative and gram-positive bacteria, contributing also to a faster regeneration of osteoblasts, fibroblasts and other types of cells for Regenerative Medicine), Growth factors (to promote the growth, organization, and maintenance of cells and tissues) and Doxorubicin (well established for chemotherapy, but reported potentially harmful for heart in the classical therapeutic approach).

Department of Silicate Technology
University of Chemical Technology and Metallurgy, BULGARIA

Dr. Chernev is an Associate Professor in Department of Silicate Technology of the University of Chemical Technology and Metallurgy, Bulgaria. Member of editorial board of the Research and Reviews in Materials Science and Chemistry and the European Journal of Materials Science and Engneering. Co-author of 60 publications with around 200 citations. His research interests are in the field of the materialis science, binding materials, chemical admixtures for concrete, geopolymers, application of waste products, low temperature method for synthesis, hybrid materials, iotechnolgy, immobilization of microorganisms.. Prof. Chernev has h-index 7 in Web of Science and 8 in Google Scollar.

*     *

A new field in the sol-gel technology is the synthesis of nanocomposite hybrid materials simultaneously containing organic and inorganic components. Such kind of materials are subject of intensively investigations because they represent significant interest for the structural chemistry and for studying their physics and chemical properties and possibilities for their applications in electronics, optics, microbiology, medicine, dentistry and pharmacology. The results from the XRD – analysis prove that all the studied hybrids have an amorphous structure. It can be see that the surface appears to be smooth and possesses no micro cavities in the samples. The results from the BET revealed that introduction of polysaccharide leads to a decrease in the surface area, but to an increase in the pore size. The surface of obtained hybrids was structurally investigated with Atomic Force Microscopy. The presence of a hybrid nanostructure with well-defined nanounits and their aggregates, with different design formed by self-organizing processes, is observed and the average size of nanoparticles is from 8 to 12 nm. The rheological characteristic of the synthesized sol gel hybrids with participation of algal polymer suggests its potential for different industrial applications, immobilization of algae and bacteria, biosorption of heavy metals and other.

Anca Daniela RAICIU
Assoc.Professor.PhD. Pharm
Marketing, Sales, Logistics & Distribution Director HOFIGAL

Ms. Chim. Anca Daniela Raiciu is a Marketing, Sales, Logistics & Distribution Director at HOFIGAL since 2007. She is also Ph.D. in Pharmaceutical Sciences, Vice President of the Romanian Society of Chemists Cosmetology Chemists, lecturer at “TITU MAIORESCU” Pharmacy. He has proudly been HOFIGAL since 2002 and has been actively involved in the creation of new products and their promotion on the domestic and foreign markets. She also has a vast experience in the pharmaceutical and cosmetic industry since 1988, and she pass through all stages of research and production.
“The fact that nothing is more important in life than health is an old wisdom, the truth of which we convince the passing day. What we need to do to acquire and maintain this precious health is a question that has marked my meaning and course of life. That led me to use my time and energy in-depth studies of chemistry, biochemistry and pharmacy and led me to get my doctorate in an increasingly interdisciplinary field.”

*     *

Gemmotherapy, also known as Phytoembryotherapy, is a modern homeopathic method of biotherapeutic drainage using the extracts of various trees and shrubs. The raw material of the buds, emerging shoots, seeds, rootlets and saps is taken at the peak time of the plant’s annual germination.
Plants are harvested in the spring, throughout the period of cellular division and plant growth. During this stage they contain the highest concentration of active growth factor hormones, auxins, and gibberellins. These specific hormonal agents contain valuable informative matter required for the drainage of various organs and tissues at the cellular level. In order to extract the embryonic substance from the fresh buds, the complex remedies are macerated for increased patient compliance.
Gemmotherapy is very popular in European countries such as France, Belgium, Italy, Germany and in some areas of Eastern Europe. It works great for skin conditions, seasonal allergies, chronic ENT’s, asthma, UTIs, migraines, digestive disturbances, sleep difficulties, menstrual irregularities, fertility issues, high blood pressure and many more.

Department of Materials Engineering
Ben-Gurion University of the Negev, ISRAEL

Dan Eliezer received his PhD in Materials Science and Engineering from the Technion Institute of Technology in Israel. He was a Research Associate at the University of Illinois at Urbana-Champaign and shortly after joined the NASA-AMES Research Center. He was a National Research Council Senior Associate at the Air Force Base in Dayton, Ohio. He was the Head of the Department of Materials Engineering and part of highly ranked administrative committees at Ben-Gurion University. He was a Senior Visiting Scientist at BAM, the Federal Institute for Materials Research in Berlin, Germany and received the prestigious Oswald Fellowship. Professor Eliezer is especially known for his research in the field of hydrogen interaction in materials. His research work also covers physical metallurgy and environmental behavior of materials. Prof. Eliezer has published over 500 papers, written numerous collective volumes, and edited 9 scientific books. Prof. Eliezer has a h-index of 37 and a RG of 44.15. He is an active member in a variety of academic, research, and institutional committees. He is also active in international advisory boards for scientific, academic, and insutrial institutions. He is the recipient of many awards and fellowships.

*     *

Development and validation of a lifetime prediction methodology for failure of materials used for hydrogen containment components is of significant importance to the planned hydrogen economy. With the prospect of transitioning to a hydrogen-based economy, many engineering components will be exposed to hydrogen environments. Hydrogen embrittlement is a severe environmental type of failure; when hydrogen is present, materials fail at load levels that are very low compared with those that a hydrogen free material can sustain. We will review recent contributions to the understanding of mechanisms of hydrogen embrittlement. The role of hydrogen in different structural materials with an emphasis on steels, titanium, and magnesium alloys will be discussed in detail. The residual stress state in a material has an important role in the mechanism of cracking, induced or assisted by hydrogen. The hydrogen interaction with residual stresses is studied by synchrotron x-ray diffraction. ToF-SIMS analyses have been optimized by achieving a spatial resolution below 100 nm. Thermal desorption spectroscopy (TDS) was used to identify and quantify the types and strengths of the hydrogen trapping sites. TDS results support the notion that only the diffusible hydrogen through the lattice sites or the hydrogen residing at the traps with the lowest binding energy contributes to material embrittlement. We present a model for hydrogen transport that accounts for trapping of hydrogen at microstructural defects and address the interaction of hydrogen solute atoms with material deformation.

Nor Aida ZUBIR
Senior Lecturer PhD.
Faculty of Chemical Engineering
Universiti Teknologi MARA (UiTM), MALAYSIA


Dr. Nor Aida is a senior lecturer in chemical engineering and head of Hybrid Nanomaterials, Interfaces & Simulation (HYMFAST) research group at Faculty of Chemical Engineering, Universiti Teknologi MARA (UiTM), Malaysia. Previously, Dr Nor Aida served as Head of Centre at the Faculty of Chemical Engineering. She has receved Doctor of Philosophy in Chemical Engineering from The University of Queensland Australia. She has an experience of 6 years in research, focusing in the field of catalysis (advanced oxidation processes and materials) for waterwater remediation. She has published over 20 research papers in various national and international journals including Chemical Communications, Scientific Reports, Journal of Membrane Sciences and as well as conference proceedings. Dr Nor Aida h-Index in Google Scholar is 9 and in Scopus is 7 with Total Citation Index of 472 and 363, respectively until Jan. 2018.

*     *

Development of active and stable heterogeneous Fenton-like catalysts have emerged as an alternative to overcome the practical limitations related to the homogeneous Fenton catalyst, where various iron species and/or iron oxides are immobilised within the structure of different catalyst supports. Clay, alumina, zeolite and carbonaceous materials such as activated carbon and carbon nanotubes have been used as catalyst supports of choice by the scientific community. However, there is a knowledge gap associated with using high aspect ratio 2D (dimension) graphene oxide (GO) as an alternative catalyst support. Of particular interest, it is postulated that the structure and functionalities of GO as a support confers to the resultant catalyst overall catalytic activity beyond the conventional Fenton catalysts. Hence, in this presentation, development of graphene oxide-iron oxide nanocomposites as promising heterogeneous Fenton-like catalysts for wastewater remediation will be presented.